My Pontiac Vibe's radio has no "aux in" or iPod connector, so I have to stream my iPhone music to it via an FM transmitter. The one I have works fine, but as with all such devices I have to put up with GSM interference when the iPhone "phones home" to check for voice messages, etc. Finally, someone is coming out with a device that filters out the interference and will allow a full iPhone transmitting experience.
Of course having an Aux In or iPod Connector in your car is a better solution, but I don't want to spend several hundred dollars on a replacement radio or several thousand on a new car. And I am no audiophile.